C3AR1 Antikörper

Produktnummer ABIN110596

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch C3AR1 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für C3AR1 Antikörper (ABIN110596)

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C3AR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktdetails anti-C3AR1 Antikörper

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Lagerung: 4 °C

Details zu C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Andere Bezeichnung: C3a Receptor

Hintergrund: C3a is an anaphylatoxin generated through activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains1,2. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains3. The loop can be readily detected using the rabbit anti-C3a receptor antibody.

Pathways: Komplementsystem